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The Bacterial Amyloids Phenol Soluble Modulins from Staphylococcus aureus Catalyze Alpha-Synuclein Aggregation

Aggregated α-synuclein (α-syn) is the main constituent of Lewy bodies, which are a pathological hallmark of Parkinson’s disease (PD). Environmental factors are thought to be potential triggers capable of initiating the aggregation of the otherwise monomeric α-syn. Braak’s seminal work redirected att...

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Detalles Bibliográficos
Autores principales: Haikal, Caroline, Ortigosa-Pascual, Lei, Najarzadeh, Zahra, Bernfur, Katja, Svanbergsson, Alexander, Otzen, Daniel E., Linse, Sara, Li, Jia-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584152/
https://www.ncbi.nlm.nih.gov/pubmed/34769023
http://dx.doi.org/10.3390/ijms222111594