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Semi-Automated High-Throughput Substrate Screening Assay for Nucleoside Kinases
Nucleoside kinases (NKs) are key enzymes involved in the in vivo phosphorylation of nucleoside analogues used as drugs to treat cancer or viral infections. Having different specificities, the characterization of NKs is essential for drug design and nucleotide analogue production in an in vitro enzym...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584170/ https://www.ncbi.nlm.nih.gov/pubmed/34768989 http://dx.doi.org/10.3390/ijms222111558 |