Hsp90 Inhibition: A Promising Therapeutic Approach for ARSACS

Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a neurodegenerative disease caused by mutations in the SACS gene, encoding the 520 kDa modular protein sacsin, which comprises multiple functional sequence domains that suggest a role either as a scaffold in protein folding or in...

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Detalles Bibliográficos
Autores principales: Nethisinghe, Suran, Abeti, Rosella, Kesavan, Maheswaran, Wigley, W. Christian, Giunti, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584178/
https://www.ncbi.nlm.nih.gov/pubmed/34769152
http://dx.doi.org/10.3390/ijms222111722

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584178/
https://www.ncbi.nlm.nih.gov/pubmed/34769152
http://dx.doi.org/10.3390/ijms222111722

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