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Hsp90 Inhibition: A Promising Therapeutic Approach for ARSACS
Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a neurodegenerative disease caused by mutations in the SACS gene, encoding the 520 kDa modular protein sacsin, which comprises multiple functional sequence domains that suggest a role either as a scaffold in protein folding or in...
Autores principales: | Nethisinghe, Suran, Abeti, Rosella, Kesavan, Maheswaran, Wigley, W. Christian, Giunti, Paola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584178/ https://www.ncbi.nlm.nih.gov/pubmed/34769152 http://dx.doi.org/10.3390/ijms222111722 |
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