Rho/ROCK Pathway and Noncoding RNAs: Implications in Ischemic Stroke and Spinal Cord Injury

Ischemic strokes (IS) and spinal cord injuries (SCI) are major causes of disability. RhoA is a small GTPase protein that activates a downstream effector, ROCK. The up-regulation of the RhoA/ROCK pathway contributes to neuronal apoptosis, neuroinflammation, blood-brain barrier dysfunction, astroglios...

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Detalles Bibliográficos
Autores principales: Kimura, Tetsu, Horikoshi, Yuta, Kuriyagawa, Chika, Niiyama, Yukitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584200/
https://www.ncbi.nlm.nih.gov/pubmed/34769004
http://dx.doi.org/10.3390/ijms222111573

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584200/
https://www.ncbi.nlm.nih.gov/pubmed/34769004
http://dx.doi.org/10.3390/ijms222111573

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