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Rho/ROCK Pathway and Noncoding RNAs: Implications in Ischemic Stroke and Spinal Cord Injury
Ischemic strokes (IS) and spinal cord injuries (SCI) are major causes of disability. RhoA is a small GTPase protein that activates a downstream effector, ROCK. The up-regulation of the RhoA/ROCK pathway contributes to neuronal apoptosis, neuroinflammation, blood-brain barrier dysfunction, astroglios...
Autores principales: | Kimura, Tetsu, Horikoshi, Yuta, Kuriyagawa, Chika, Niiyama, Yukitoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584200/ https://www.ncbi.nlm.nih.gov/pubmed/34769004 http://dx.doi.org/10.3390/ijms222111573 |
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