Fluoroquinolones Suppress TGF-β and PMA-Induced MMP-9 Production in Cancer Cells: Implications in Repurposing Quinolone Antibiotics for Cancer Treatment

Background: Fluoroquinolones (FQs) are potent antimicrobials with multiple effects on host cells and tissues. Although FQs can attenuate cancer invasion and metastasis, the underlying molecular mechanisms remain unclear. Matrix metalloproteinase-9 (MMP-9) has functional roles in tumor angiogenesis,...

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Detalles Bibliográficos
Autores principales: Huang, Cheng-Yi, Yang, Jenq-Lin, Chen, Jih-Jung, Tai, Shun-Ban, Yeh, Yu-Hsuan, Liu, Pei-Feng, Lin, Ming-Wei, Chung, Chih-Ling, Chen, Chun-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584204/
https://www.ncbi.nlm.nih.gov/pubmed/34769032
http://dx.doi.org/10.3390/ijms222111602

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584204/
https://www.ncbi.nlm.nih.gov/pubmed/34769032
http://dx.doi.org/10.3390/ijms222111602

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