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Fluoroquinolones Suppress TGF-β and PMA-Induced MMP-9 Production in Cancer Cells: Implications in Repurposing Quinolone Antibiotics for Cancer Treatment
Background: Fluoroquinolones (FQs) are potent antimicrobials with multiple effects on host cells and tissues. Although FQs can attenuate cancer invasion and metastasis, the underlying molecular mechanisms remain unclear. Matrix metalloproteinase-9 (MMP-9) has functional roles in tumor angiogenesis,...
Autores principales: | Huang, Cheng-Yi, Yang, Jenq-Lin, Chen, Jih-Jung, Tai, Shun-Ban, Yeh, Yu-Hsuan, Liu, Pei-Feng, Lin, Ming-Wei, Chung, Chih-Ling, Chen, Chun-Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584204/ https://www.ncbi.nlm.nih.gov/pubmed/34769032 http://dx.doi.org/10.3390/ijms222111602 |
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