Aberrant Mitochondrial Dynamics and Exacerbated Response to Neuroinflammation in a Novel Mouse Model of CMT2A

Charcot-Marie-Tooth disease type 2A (CMT2A) is the most common hereditary axonal neuropathy caused by mutations in MFN2 encoding Mitofusin-2, a multifunctional protein located in the outer mitochondrial membrane. In order to study the effects of a novel MFN2(K357T) mutation associated with early ons...

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Detalles Bibliográficos
Autores principales: Stavropoulos, Filippos, Sargiannidou, Irene, Potamiti, Louiza, Kagiava, Alexia, Panayiotidis, Mihalis I., Bae, Ji Hyun, Yeom, Su Cheong, Lee, Jae Young, Kleopa, Kleopas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584238/
https://www.ncbi.nlm.nih.gov/pubmed/34769001
http://dx.doi.org/10.3390/ijms222111569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584238/
https://www.ncbi.nlm.nih.gov/pubmed/34769001
http://dx.doi.org/10.3390/ijms222111569

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