Increased Collagen Crosslinking in Stiff Clubfoot Tissue: Implications for the Improvement of Therapeutic Strategies

Congenital clubfoot is a complex musculoskeletal deformity, in which a stiff, contracted tissue forms in the medial part of the foot. Fibrotic changes are associated with increased collagen deposition and lysyl oxidase (LOX)-mediated crosslinking, which impair collagen degradation and increase the t...

Descripción completa

Detalles Bibliográficos
Autores principales: Knitlova, Jarmila, Doubkova, Martina, Eckhardt, Adam, Ostadal, Martin, Musilkova, Jana, Bacakova, Lucie, Novotny, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584281/
https://www.ncbi.nlm.nih.gov/pubmed/34769331
http://dx.doi.org/10.3390/ijms222111903

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584281/
https://www.ncbi.nlm.nih.gov/pubmed/34769331
http://dx.doi.org/10.3390/ijms222111903

Ejemplares similares