Activation of ERK and p38 Reduces AZD8055-Mediated Inhibition of Protein Synthesis in Hepatocellular Carcinoma HepG2 Cell Line

Protein synthesis is important for maintaining cellular homeostasis under various stress responses. In this study, we screened an anticancer drug library to select compounds with translational repression functions. AZD8055, an ATP-competitive mechanistic target of rapamycin complex 1/2 (mTORC1/2) in...

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Detalles Bibliográficos
Autores principales: Jee, Ha-yeon, Lee, Yoon-Gyeong, Lee, Sol, Elvira, Rosalie, Seo, Hye-eun, Lee, Ji-Yeon, Han, Jaeseok, Lee, Kyungho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584319/
https://www.ncbi.nlm.nih.gov/pubmed/34769253
http://dx.doi.org/10.3390/ijms222111824

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584319/
https://www.ncbi.nlm.nih.gov/pubmed/34769253
http://dx.doi.org/10.3390/ijms222111824

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