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Genetic Variation in ABCC4 and CFTR and Acute Pancreatitis during Treatment of Pediatric Acute Lymphoblastic Leukemia

Background: Acute pancreatitis (AP) is a serious, mechanistically not entirely resolved side effect of L-asparaginase-containing treatment for acute lymphoblastic leukemia (ALL). To find new candidate variations for AP, we conducted a genome-wide association study (GWAS). Methods: In all, 1,004,623...

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Detalles Bibliográficos
Autores principales: Bartram, Thies, Schütte, Peter, Möricke, Anja, Houlston, Richard S., Ellinghaus, Eva, Zimmermann, Martin, Bergmann, Anke, Löscher, Britt-Sabina, Klein, Norman, Hinze, Laura, Junk, Stefanie V., Forster, Michael, Bartram, Claus R., Köhler, Rolf, Franke, Andre, Schrappe, Martin, Kratz, Christian P., Cario, Gunnar, Stanulla, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584334/
https://www.ncbi.nlm.nih.gov/pubmed/34768335
http://dx.doi.org/10.3390/jcm10214815