A Novel Isogenic Human Cell-Based System for MEN1 Syndrome Generated by CRISPR/Cas9 Genome Editing

Multiple endocrine neoplasia type 1 (MEN1) is a rare tumor syndrome that manifests differently among various patients. Despite the mutations in the MEN1 gene that commonly predispose tumor development, there are no obvious phenotype–genotype correlations. The existing animal and in vitro models do n...

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Detalles Bibliográficos
Autores principales: Klementieva, Natalia, Goliusova, Daria, Krupinova, Julia, Yanvarev, Vladislav, Panova, Alexandra, Mokrysheva, Natalia, Kiselev, Sergey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584395/
https://www.ncbi.nlm.nih.gov/pubmed/34769484
http://dx.doi.org/10.3390/ijms222112054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584395/
https://www.ncbi.nlm.nih.gov/pubmed/34769484
http://dx.doi.org/10.3390/ijms222112054

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