Tofacitinib Ameliorates Retinal Vascular Leakage in a Murine Model of Diabetic Retinopathy with Type 2 Diabetes

We have previously reported that inhibition of the Janus kinase 1 (JAK1) signaling ameliorates IL-17A-mediated blood-retinal barrier (BRB) dysfunction. Higher levels of IL-17A have been observed in the blood and intraocular fluids in patients with diabetic retinopathy (DR), in particular those with...

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Detalles Bibliográficos
Autores principales: Byrne, Eimear M., Llorián-Salvador, María, Lyons, Timothy J., Chen, Mei, Xu, Heping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584492/
https://www.ncbi.nlm.nih.gov/pubmed/34769307
http://dx.doi.org/10.3390/ijms222111876

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584492/
https://www.ncbi.nlm.nih.gov/pubmed/34769307
http://dx.doi.org/10.3390/ijms222111876

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