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Tofacitinib Ameliorates Retinal Vascular Leakage in a Murine Model of Diabetic Retinopathy with Type 2 Diabetes
We have previously reported that inhibition of the Janus kinase 1 (JAK1) signaling ameliorates IL-17A-mediated blood-retinal barrier (BRB) dysfunction. Higher levels of IL-17A have been observed in the blood and intraocular fluids in patients with diabetic retinopathy (DR), in particular those with...
Autores principales: | Byrne, Eimear M., Llorián-Salvador, María, Lyons, Timothy J., Chen, Mei, Xu, Heping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584492/ https://www.ncbi.nlm.nih.gov/pubmed/34769307 http://dx.doi.org/10.3390/ijms222111876 |
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