CRISPRi-Guided Metabolic Flux Engineering for Enhanced Protopanaxadiol Production in Saccharomyces cerevisiae

Protopanaxadiol (PPD), an aglycon found in several dammarene-type ginsenosides, has high potency as a pharmaceutical. Nevertheless, application of these ginsenosides has been limited because of the high production cost due to the rare content of PPD in Panax ginseng and a long cultivation time (4–6...

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Detalles Bibliográficos
Autores principales: Lim, Soo-Hwan, Baek, Jong-In, Jeon, Byeong-Min, Seo, Jung-Woo, Kim, Min-Sung, Byun, Ji-Young, Park, Soo-Hoon, Kim, Su-Jin, Lee, Ju-Young, Lee, Jun-Hyoung, Kim, Sun-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584524/
https://www.ncbi.nlm.nih.gov/pubmed/34769267
http://dx.doi.org/10.3390/ijms222111836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584524/
https://www.ncbi.nlm.nih.gov/pubmed/34769267
http://dx.doi.org/10.3390/ijms222111836

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