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CRISPRi-Guided Metabolic Flux Engineering for Enhanced Protopanaxadiol Production in Saccharomyces cerevisiae
Protopanaxadiol (PPD), an aglycon found in several dammarene-type ginsenosides, has high potency as a pharmaceutical. Nevertheless, application of these ginsenosides has been limited because of the high production cost due to the rare content of PPD in Panax ginseng and a long cultivation time (4–6...
Autores principales: | Lim, Soo-Hwan, Baek, Jong-In, Jeon, Byeong-Min, Seo, Jung-Woo, Kim, Min-Sung, Byun, Ji-Young, Park, Soo-Hoon, Kim, Su-Jin, Lee, Ju-Young, Lee, Jun-Hyoung, Kim, Sun-Chang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584524/ https://www.ncbi.nlm.nih.gov/pubmed/34769267 http://dx.doi.org/10.3390/ijms222111836 |
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