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Amyloid-Driven Tau Accumulation on Mitochondria Potentially Leads to Cognitive Deterioration in Alzheimer’s Disease

Despite the well-accepted role of the two main neuropathological markers (β-amyloid and tau) in the progression of Alzheimer’s disease, the interaction and specific contribution of each of them is not fully elucidated. To address this question, in the present study, an adeno-associated virus (AAV9)...

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Detalles Bibliográficos
Autores principales: Cuadrado-Tejedor, Mar, Pérez-González, Marta, Alfaro-Ruiz, Rocío, Badesso, Sara, Sucunza, Diego, Espelosin, María, Ursúa, Susana, Lachen-Montes, Mercedes, Fernández-Irigoyen, Joaquín, Santamaria, Enrique, Luján, Rafael, García-Osta, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584544/
https://www.ncbi.nlm.nih.gov/pubmed/34769380
http://dx.doi.org/10.3390/ijms222111950