Old and New Calcineurin Inhibitors in Lupus Nephritis

Calcineurin inhibitors (CNIs) are drugs that inhibit calcineurin, a key phosphatase that dephosphorylates a transcription factor called the nuclear factor of activated T cells (NFAT), allowing its translocation into the nucleus of quiescent T cells. In the nucleus, NFAT activates interleukin 2, whic...

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Detalles Bibliográficos
Autores principales: Ponticelli, Claudio, Reggiani, Francesco, Moroni, Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584552/
https://www.ncbi.nlm.nih.gov/pubmed/34768354
http://dx.doi.org/10.3390/jcm10214832

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584552/
https://www.ncbi.nlm.nih.gov/pubmed/34768354
http://dx.doi.org/10.3390/jcm10214832

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