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A Novel Method of Mouse RPE Explant Culture and Effective Introduction of Transgenes Using Adenoviral Transduction for In Vitro Studies in AMD

Degeneration of retinal pigment epithelium (RPE) is one of the most critical phenotypic changes of age-related macular degeneration (AMD), the leading cause of vision loss in the elderly. While cultured polarized RPE cells with original properties are valuable in in vitro models to study RPE biology...

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Detalles Bibliográficos
Autores principales: Shang, Peng, Stepicheva, Nadezda A., Liu, Haitao, Chowdhury, Olivia, Franks, Jonathan, Sun, Ming, Hose, Stacey, Ghosh, Sayan, Yazdankhah, Meysam, Strizhakova, Anastasia, Stolz, Donna Beer, Zigler, J. Samuel, Sinha, Debasish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584596/
https://www.ncbi.nlm.nih.gov/pubmed/34769409
http://dx.doi.org/10.3390/ijms222111979