Induction of Premature Cell Senescence Stimulated by High Doses of Antioxidants Is Mediated by Endoplasmic Reticulum Stress

In our previous study, we found that high doses of several substances with antioxidant capacities (Tempol, resveratrol, diphenyleneiodonium) can cause genotoxic stress and induce premature senescence in the human mesenchymal stem cells (MSCs). Here, using whole-transcriptome analysis, we revealed th...

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Detalles Bibliográficos
Autores principales: Lyublinskaya, Olga, Kornienko, Julia, Ivanova, Julia, Pugovkina, Natalia, Alekseenko, Larisa, Lyublinskaya, Ekaterina, Tyuryaeva, Irina, Smirnova, Irina, Grinchuk, Tatiana, Shorokhova, Mariia, Krasnenko, Anna, Plotnikov, Nikolay, Nikolsky, Nikolay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584632/
https://www.ncbi.nlm.nih.gov/pubmed/34769282
http://dx.doi.org/10.3390/ijms222111851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584632/
https://www.ncbi.nlm.nih.gov/pubmed/34769282
http://dx.doi.org/10.3390/ijms222111851

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