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Microarray profiling predicts early neurological and immune phenotypic traits in advance of CNS disease during disease progression in Trypanosoma. b. brucei infected CD1 mouse brains

Human African trypanosomiasis (HAT), also known as sleeping sickness, is a major cause of mortality and morbidity in sub-Saharan Africa. We hypothesised that recent findings of neurological features and parasite brain infiltration occurring at much earlier stages in HAT than previously thought could...

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Detalles Bibliográficos
Autores principales: Montague, Paul, Bradley, Barbara, Rodgers, Jean, Kennedy, Peter G. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584711/
https://www.ncbi.nlm.nih.gov/pubmed/34762691
http://dx.doi.org/10.1371/journal.pntd.0009892