The Use of Inhibitors of Tyrosine Kinase in Paediatric Haemato-Oncology—When and Why?

The fundamental pathophysiology of malignancies is dysregulation of the signalling pathways. Protein tyrosine kinases (PTKs) are among the enzymes which, if mutated, play a critical role in carcinogenesis. The best-studied rearrangement, which enhances PTK activity and causes atypical proliferation,...

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Detalles Bibliográficos
Autores principales: Kaczmarska, Agnieszka, Śliwa, Patrycja, Lejman, Monika, Zawitkowska, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584725/
https://www.ncbi.nlm.nih.gov/pubmed/34769519
http://dx.doi.org/10.3390/ijms222112089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584725/
https://www.ncbi.nlm.nih.gov/pubmed/34769519
http://dx.doi.org/10.3390/ijms222112089

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