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The Use of Inhibitors of Tyrosine Kinase in Paediatric Haemato-Oncology—When and Why?
The fundamental pathophysiology of malignancies is dysregulation of the signalling pathways. Protein tyrosine kinases (PTKs) are among the enzymes which, if mutated, play a critical role in carcinogenesis. The best-studied rearrangement, which enhances PTK activity and causes atypical proliferation,...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584725/ https://www.ncbi.nlm.nih.gov/pubmed/34769519 http://dx.doi.org/10.3390/ijms222112089 |