Olaparib Is a Mitochondrial Complex I Inhibitor That Kills Temozolomide-Resistant Human Glioblastoma Cells

Glioblastoma represents the highest grade of brain tumors. Despite maximal resection surgery associated with radiotherapy and concomitant followed by adjuvant chemotherapy with temozolomide (TMZ), patients have a very poor prognosis due to the rapid recurrence and the acquisition of resistance to TM...

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Detalles Bibliográficos
Autores principales: Zampieri, Luca X., Sboarina, Martina, Cacace, Andrea, Grasso, Debora, Thabault, Léopold, Hamelin, Loïc, Vazeille, Thibaut, Dumon, Elodie, Rossignol, Rodrigue, Frédérick, Raphaël, Sonveaux, Etienne, Lefranc, Florence, Sonveaux, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584761/
https://www.ncbi.nlm.nih.gov/pubmed/34769368
http://dx.doi.org/10.3390/ijms222111938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584761/
https://www.ncbi.nlm.nih.gov/pubmed/34769368
http://dx.doi.org/10.3390/ijms222111938

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