DNA methylation-based classifier and gene expression signatures detect BRCAness in osteosarcoma

Although osteosarcoma (OS) is a rare cancer, it is the most common primary malignant bone tumor in children and adolescents. BRCAness is a phenotypical trait in tumors with a defect in homologous recombination repair, resembling tumors with inactivation of BRCA1/2, rendering these tumors sensitive t...

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Detalles Bibliográficos
Autores principales: Barenboim, Maxim, Kovac, Michal, Ameline, Baptiste, Jones, David T. W., Witt, Olaf, Bielack, Stefan, Burdach, Stefan, Baumhoer, Daniel, Nathrath, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584788/
https://www.ncbi.nlm.nih.gov/pubmed/34762643
http://dx.doi.org/10.1371/journal.pcbi.1009562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584788/
https://www.ncbi.nlm.nih.gov/pubmed/34762643
http://dx.doi.org/10.1371/journal.pcbi.1009562

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