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PI3Kinase Inhibition in Hormone Receptor-Positive Breast Cancer

Derangement of the phosphatidylinositol-3 kinase (PI3K) pathway is implicated in several subtypes of breast cancers. Mutation or upregulation of PI3K enhances cancer cells’ survival, proliferation, and ability to metastasize, making it an attractive molecular target for systemic therapy. PI3K has fo...

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Detalles Bibliográficos
Autores principales: Dhakal, Ajay, Acharya, Luna, O’Regan, Ruth, Gandhi, Shipra, Falkson, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584833/
https://www.ncbi.nlm.nih.gov/pubmed/34769309
http://dx.doi.org/10.3390/ijms222111878