MALDI-MS Analysis of Peptide Libraries Expands the Scope of Substrates for Farnesyltransferase

Protein farnesylation is a post-translational modification where a 15-carbon farnesyl isoprenoid is appended to the C-terminal end of a protein by farnesyltransferase (FTase). This modification typically causes proteins to associate with the membrane and allows them to participate in signaling pathw...

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Detalles Bibliográficos
Autores principales: Schey, Garrett L., Buttery, Peter H., Hildebrandt, Emily R., Novak, Sadie X., Schmidt, Walter K., Hougland, James L., Distefano, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584866/
https://www.ncbi.nlm.nih.gov/pubmed/34769472
http://dx.doi.org/10.3390/ijms222112042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584866/
https://www.ncbi.nlm.nih.gov/pubmed/34769472
http://dx.doi.org/10.3390/ijms222112042

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