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MALDI-MS Analysis of Peptide Libraries Expands the Scope of Substrates for Farnesyltransferase
Protein farnesylation is a post-translational modification where a 15-carbon farnesyl isoprenoid is appended to the C-terminal end of a protein by farnesyltransferase (FTase). This modification typically causes proteins to associate with the membrane and allows them to participate in signaling pathw...
Autores principales: | Schey, Garrett L., Buttery, Peter H., Hildebrandt, Emily R., Novak, Sadie X., Schmidt, Walter K., Hougland, James L., Distefano, Mark D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584866/ https://www.ncbi.nlm.nih.gov/pubmed/34769472 http://dx.doi.org/10.3390/ijms222112042 |
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