Identification of Spiro-Fused Pyrrolo[3,4-a]pyrrolizines and Tryptanthrines as Potential Antitumor Agents: Synthesis and In Vitro Evaluation

A series of heterocyclic compounds containing a spiro-fused pyrrolo[3,4-a]pyrrolizine and tryptanthrin framework have been synthesized and studied as potential antitumor agents. Cytotoxicity of products was screened against human erythroleukemia (K562) and human cervical carcinoma (HeLa) cell lines....

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Detalles Bibliográficos
Autores principales: Latypova, Diana K., Shmakov, Stanislav V., Pechkovskaya, Sofya A., Filatov, Alexander S., Stepakov, Alexander V., Knyazev, Nickolay A., Boitsov, Vitali M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584944/
https://www.ncbi.nlm.nih.gov/pubmed/34769424
http://dx.doi.org/10.3390/ijms222111997

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584944/
https://www.ncbi.nlm.nih.gov/pubmed/34769424
http://dx.doi.org/10.3390/ijms222111997

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