Human Recombinant DNase I (Pulmozyme(®)) Inhibits Lung Metastases in Murine Metastatic B16 Melanoma Model That Correlates with Restoration of the DNase Activity and the Decrease SINE/LINE and c-Myc Fragments in Blood Cell-Free DNA

Tumor-associated cell-free DNAs (cfDNA) play an important role in the promotion of metastases. Previous studies proved the high antimetastatic potential of bovine pancreatic DNase I and identified short interspersed nuclear elements (SINEs) and long interspersed nuclear elements (LINEs)and fragments...

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Detalles Bibliográficos
Autores principales: Alekseeva, Ludmila, Sen’kova, Aleksandra, Savin, Innokenty, Zenkova, Marina, Mironova, Nadezhda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585023/
https://www.ncbi.nlm.nih.gov/pubmed/34769514
http://dx.doi.org/10.3390/ijms222112074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585023/
https://www.ncbi.nlm.nih.gov/pubmed/34769514
http://dx.doi.org/10.3390/ijms222112074

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