Cargando…
Human Recombinant DNase I (Pulmozyme(®)) Inhibits Lung Metastases in Murine Metastatic B16 Melanoma Model That Correlates with Restoration of the DNase Activity and the Decrease SINE/LINE and c-Myc Fragments in Blood Cell-Free DNA
Tumor-associated cell-free DNAs (cfDNA) play an important role in the promotion of metastases. Previous studies proved the high antimetastatic potential of bovine pancreatic DNase I and identified short interspersed nuclear elements (SINEs) and long interspersed nuclear elements (LINEs)and fragments...
Autores principales: | Alekseeva, Ludmila, Sen’kova, Aleksandra, Savin, Innokenty, Zenkova, Marina, Mironova, Nadezhda |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585023/ https://www.ncbi.nlm.nih.gov/pubmed/34769514 http://dx.doi.org/10.3390/ijms222112074 |
Ejemplares similares
-
Targeting Circulating SINEs and LINEs with DNase I Provides Metastases Inhibition in Experimental Tumor Models
por: Alekseeva, Ludmila A., et al.
Publicado: (2020) -
Short-course modified regimen intrapleural alteplase and pulmozyme (DNase) in pleural infection
por: Faisal, M., et al.
Publicado: (2020) -
Low dose intrapleural alteplase and pulmozyme (DNase) in two post-surgical patients with pleural sepsis
por: Faisal, M., et al.
Publicado: (2020) -
Alteration of the exDNA profile in blood serum of LLC-bearing mice under the decrease of tumour invasion potential by bovine pancreatic DNase I treatment
por: Alekseeva, Ludmila A., et al.
Publicado: (2017) -
Pulmonary Fibrosis as a Result of Acute Lung Inflammation: Molecular Mechanisms, Relevant In Vivo Models, Prognostic and Therapeutic Approaches
por: Savin, Innokenty A., et al.
Publicado: (2022)