Inhibitors of the Sec61 Complex and Novel High Throughput Screening Strategies to Target the Protein Translocation Pathway

Proteins targeted to the secretory pathway start their intracellular journey by being transported across biological membranes such as the endoplasmic reticulum (ER). A central component in this protein translocation process across the ER is the Sec61 translocon complex, which is only intracellularly...

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Detalles Bibliográficos
Autores principales: Pauwels, Eva, Schülein, Ralf, Vermeire, Kurt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585047/
https://www.ncbi.nlm.nih.gov/pubmed/34769437
http://dx.doi.org/10.3390/ijms222112007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585047/
https://www.ncbi.nlm.nih.gov/pubmed/34769437
http://dx.doi.org/10.3390/ijms222112007

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