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Pleiotropic Roles of NOTCH1 Signaling in the Loss of Maturational Arrest of Human Osteoarthritic Chondrocytes

Notch signaling has been identified as a critical regulator of cartilage development and homeostasis. Its pivotal role was established by both several joint specific Notch signaling loss of function mouse models and transient or sustained overexpression. NOTCH1 is the most abundantly expressed NOTCH...

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Detalles Bibliográficos
Autores principales: Minguzzi, Manuela, Panichi, Veronica, D’Adamo, Stefania, Cetrullo, Silvia, Cattini, Luca, Flamigni, Flavio, Mariani, Erminia, Borzì, Rosa Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585104/
https://www.ncbi.nlm.nih.gov/pubmed/34769441
http://dx.doi.org/10.3390/ijms222112012