Cargando…
Pleiotropic Roles of NOTCH1 Signaling in the Loss of Maturational Arrest of Human Osteoarthritic Chondrocytes
Notch signaling has been identified as a critical regulator of cartilage development and homeostasis. Its pivotal role was established by both several joint specific Notch signaling loss of function mouse models and transient or sustained overexpression. NOTCH1 is the most abundantly expressed NOTCH...
Autores principales: | Minguzzi, Manuela, Panichi, Veronica, D’Adamo, Stefania, Cetrullo, Silvia, Cattini, Luca, Flamigni, Flavio, Mariani, Erminia, Borzì, Rosa Maria |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585104/ https://www.ncbi.nlm.nih.gov/pubmed/34769441 http://dx.doi.org/10.3390/ijms222112012 |
Ejemplares similares
-
“Spermidine restores dysregulated autophagy and polyamine synthesis in aged and osteoarthritic chondrocytes via EP300”
por: Borzì, Rosa Maria, et al.
Publicado: (2019) -
Emerging Players at the Intersection of Chondrocyte Loss of Maturational Arrest, Oxidative Stress, Senescence and Low-Grade Inflammation in Osteoarthritis
por: Minguzzi, Manuela, et al.
Publicado: (2018) -
NOTCH1: A Novel Player in the Molecular Crosstalk Underlying Articular Chondrocyte Protection by Oleuropein and Hydroxytyrosol
por: Panichi, Veronica, et al.
Publicado: (2023) -
MicroRNAs and Autophagy: Fine Players in the Control of Chondrocyte Homeostatic Activities in Osteoarthritis
por: D'Adamo, Stefania, et al.
Publicado: (2017) -
Nutraceutical Activity in Osteoarthritis Biology: A Focus on the Nutrigenomic Role
por: D’Adamo, Stefania, et al.
Publicado: (2020)