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Optimized Rivastigmine Nanoparticles Coated with Eudragit for Intranasal Application to Brain Delivery: Evaluation and Nasal Ciliotoxicity Studies

Rivastigmine, a reversible cholinesterase inhibitor, is frequently indicated in the management of demented conditions associated with Alzheimer disease. The major hurdle of delivering this drug through the oral route is its poor bioavailability, which prompted the development of novel delivery appro...

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Detalles Bibliográficos
Autores principales: Bhanderi, Mansi, Shah, Jigar, Gorain, Bapi, Nair, Anroop B., Jacob, Shery, Asdaq, Syed Mohammed Basheeruddin, Fattepur, Santosh, Alamri, Abdulhakeem S., Alsanie, Walaa F., Alhomrani, Majid, Nagaraja, Sreeharsha, Anwer, Md. Khalid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585143/
https://www.ncbi.nlm.nih.gov/pubmed/34771817
http://dx.doi.org/10.3390/ma14216291