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Therapeutic Actionability of Circulating Cell-Free DNA Alterations in Carcinoma of Unknown Primary

Cancer of unknown primary (CUP) is a metastatic disease with unidentifiable primary tumor. Somatic alterations can be assessed noninvasively via liquid biopsies interrogating cell-free DNA (cfDNA). METHODS: We evaluated 1,931 patients with CUP with a cfDNA next-generation sequencing panel (73-74 gen...

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Detalles Bibliográficos
Autores principales: Kato, Shumei, Weipert, Caroline, Gumas, Sophia, Okamura, Ryosuke, Lee, Suzanna, Sicklick, Jason K., Saam, Jennifer, Kurzrock, Razelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585281/
https://www.ncbi.nlm.nih.gov/pubmed/34778692
http://dx.doi.org/10.1200/PO.21.00011