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Combination of ebselen and hydrocortisone substantially reduces nitrogen mustard-induced cutaneous injury

The purpose of the present study was to investigate the vesicant countermeasure effects of hydrocortisone (HC) and ebselen (EB-1), administered as monotherapy or as a combination treatment. The mouse ear vesicant model (MEVM) was utilized and test doses of HC (0.016, 0.023, 0.031, 0.047, 0.063, 0.12...

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Detalles Bibliográficos
Autores principales: Tumu, Hemanta C Rao, Cuffari, Benedette J., Billack, Blase
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585582/
https://www.ncbi.nlm.nih.gov/pubmed/34806038
http://dx.doi.org/10.1016/j.crtox.2021.10.002