Ionizing irradiation-induced Fgr in senescent cells mediates fibrosis

The role of cellular senescence in radiation-induced pulmonary fibrosis (RIPF) and the underlying mechanisms are unknown. We isolated radiation-induced senescent tdTOMp16 positive mesenchymal stem cells, established their absence of cell division, then measured levels of irradiation-induced expressi...

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Detalles Bibliográficos
Autores principales: Mukherjee, Amitava, Epperly, Michael W., Shields, Donna, Hou, Wen, Fisher, Renee, Hamade, Diala, Wang, Hong, Saiful Huq, M., Bao, Riyue, Tabib, Tracy, Monier, Daisy, Watkins, Simon, Calderon, Michael, Greenberger, Joel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585734/
https://www.ncbi.nlm.nih.gov/pubmed/34772919
http://dx.doi.org/10.1038/s41420-021-00741-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585734/
https://www.ncbi.nlm.nih.gov/pubmed/34772919
http://dx.doi.org/10.1038/s41420-021-00741-4

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