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Activated Protein C Ameliorates Diabetic Cardiomyopathy via Modulating OTUB1/YB-1/MEF2B Axis

Aims: The pathogenesis of diabetic cardiomyopathy (DCM) is complex and the detailed mechanism remains unclear. Coagulation protease activated Protein C (aPC) has been reported to have a protective effect in diabetic microvascular disease. Here, we investigated whether aPC could play a protective rol...

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Detalles Bibliográficos
Autores principales: Zhong, Xiaodan, Wang, Tao, Xie, Yang, Wang, Mengwen, Zhang, Wenjun, Dai, Lei, Lai, Jinsheng, Nie, Xiang, He, Xingwei, Madhusudhan, Thati, Zeng, Hesong, Wang, Hongjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585767/
https://www.ncbi.nlm.nih.gov/pubmed/34778410
http://dx.doi.org/10.3389/fcvm.2021.758158