Validation of a Population Pharmacokinetic Model of Vortioxetine Using Therapeutic Drug Monitoring Data

INTRODUCTION: Vortioxetine is an antidepressant primarily metabolized by the polymorphic enzyme cytochrome P450 (CYP) 2D6. A population pharmacokinetic (popPK) model of vortioxetine and its CYP2D6-dependent metabolite was recently published. OBJECTIVE: The aim of the current study was to assess the...

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Detalles Bibliográficos
Autores principales: Frederiksen, Trine, Smith, Robert L., Wollmann, Birgit M., Areberg, Johan, Molden, Espen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585800/
https://www.ncbi.nlm.nih.gov/pubmed/34121163
http://dx.doi.org/10.1007/s40262-021-01029-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585800/
https://www.ncbi.nlm.nih.gov/pubmed/34121163
http://dx.doi.org/10.1007/s40262-021-01029-7

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