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Pharmacokinetics and Associated Efficacy of Emicizumab in Humans: A Systematic Review

INTRODUCTION: Emicizumab is an effective new treatment option for people with hemophilia A (PwHA). The approved dosing regimens are based on body weight, without the necessity for laboratory monitoring. This assumes a clear dose–concentration–response relationship, with acceptable variability due to...

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Detalles Bibliográficos
Autores principales: Donners, Anouk A. M. T., Rademaker, Carin M. A., Bevers, Lisanne A. H., Huitema, Alwin D. R., Schutgens, Roger E. G., Egberts, Toine C. G., Fischer, Kathelijn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585815/
https://www.ncbi.nlm.nih.gov/pubmed/34389928
http://dx.doi.org/10.1007/s40262-021-01042-w