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Metabolomic Analysis Reveals the Therapeutic Effects of MBT1805, a Novel Pan-Peroxisome Proliferator-Activated Receptor Agonist, on α-Naphthylisothiocyanate-Induced Cholestasis in Mice

Background and Aims: Therapeutic drugs that are used to treat cholestatic liver disease are limited; however, the results of clinical trials on primary biliary cholangitis treatment targeting peroxisome proliferator-activated receptors (PPARs) are encouraging. In this study, we aimed to identify the...

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Detalles Bibliográficos
Autores principales: Wang, Chang, Peng, Fei, Zhong, Bohua, Shi, Ying, Wang, Xiaomei, Jin, Xueyuan, Niu, Junqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585842/
https://www.ncbi.nlm.nih.gov/pubmed/34776958
http://dx.doi.org/10.3389/fphar.2021.732478