A modular toolbox to generate complex polymeric ubiquitin architectures using orthogonal sortase enzymes

The post-translational modification of proteins with ubiquitin (Ub) and Ub-like modifiers (Ubls) represents one of the most important regulators in eukaryotic biology. Polymeric Ub/Ubl chains of distinct topologies control the activity, stability, interaction and localization of almost all cellular...

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Detalles Bibliográficos
Autores principales: Fottner, Maximilian, Weyh, Maria, Gaussmann, Stefan, Schwarz, Dominic, Sattler, Michael, Lang, Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585875/
https://www.ncbi.nlm.nih.gov/pubmed/34764289
http://dx.doi.org/10.1038/s41467-021-26812-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585875/
https://www.ncbi.nlm.nih.gov/pubmed/34764289
http://dx.doi.org/10.1038/s41467-021-26812-9

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