Introns control stochastic allele expression bias

Monoallelic expression (MAE) or extreme allele bias can account for incomplete penetrance, missing heritability and non-Mendelian diseases. In cancer, MAE is associated with shorter patient survival times and higher tumor grade. Prior studies showed that stochastic MAE is caused by stochastic epigen...

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Detalles Bibliográficos
Autores principales: Sands, Bryan, Yun, Soo, Mendenhall, Alexander R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585970/
https://www.ncbi.nlm.nih.gov/pubmed/34764277
http://dx.doi.org/10.1038/s41467-021-26798-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585970/
https://www.ncbi.nlm.nih.gov/pubmed/34764277
http://dx.doi.org/10.1038/s41467-021-26798-4

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