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Acute myeloid leukemia maturation lineage influences residual disease and relapse following differentiation therapy

Acute myeloid leukemia (AML) is a malignancy of immature progenitor cells. AML differentiation therapies trigger leukemia maturation and can induce remission, but relapse is prevalent and its cellular origin is unclear. Here we describe high resolution analysis of differentiation therapy response an...

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Detalles Bibliográficos
Autores principales: Ngo, Steven, Oxley, Ethan P., Ghisi, Margherita, Garwood, Maximilian M., McKenzie, Mark D., Mitchell, Helen L., Kanellakis, Peter, Susanto, Olivia, Hickey, Michael J., Perkins, Andrew C., Kile, Benjamin T., Dickins, Ross A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586014/
https://www.ncbi.nlm.nih.gov/pubmed/34764270
http://dx.doi.org/10.1038/s41467-021-26849-w