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Acute myeloid leukemia maturation lineage influences residual disease and relapse following differentiation therapy
Acute myeloid leukemia (AML) is a malignancy of immature progenitor cells. AML differentiation therapies trigger leukemia maturation and can induce remission, but relapse is prevalent and its cellular origin is unclear. Here we describe high resolution analysis of differentiation therapy response an...
Autores principales: | Ngo, Steven, Oxley, Ethan P., Ghisi, Margherita, Garwood, Maximilian M., McKenzie, Mark D., Mitchell, Helen L., Kanellakis, Peter, Susanto, Olivia, Hickey, Michael J., Perkins, Andrew C., Kile, Benjamin T., Dickins, Ross A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586014/ https://www.ncbi.nlm.nih.gov/pubmed/34764270 http://dx.doi.org/10.1038/s41467-021-26849-w |
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