CENP-V is required for proper chromosome segregation through interaction with spindle microtubules in mouse oocytes

Proper chromosome segregation is essential to avoid aneuploidy, yet this process fails with increasing age in mammalian oocytes. Here we report a role for the scarcely described protein CENP-V in oocyte spindle formation and chromosome segregation. We show that depending on the oocyte maturation sta...

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Detalles Bibliográficos
Autores principales: Nabi, Dalileh, Drechsler, Hauke, Pschirer, Johannes, Korn, Franz, Schuler, Nadine, Diez, Stefan, Jessberger, Rolf, Chacón, Mariola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586017/
https://www.ncbi.nlm.nih.gov/pubmed/34764261
http://dx.doi.org/10.1038/s41467-021-26826-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586017/
https://www.ncbi.nlm.nih.gov/pubmed/34764261
http://dx.doi.org/10.1038/s41467-021-26826-3

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