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CENP-V is required for proper chromosome segregation through interaction with spindle microtubules in mouse oocytes
Proper chromosome segregation is essential to avoid aneuploidy, yet this process fails with increasing age in mammalian oocytes. Here we report a role for the scarcely described protein CENP-V in oocyte spindle formation and chromosome segregation. We show that depending on the oocyte maturation sta...
Autores principales: | Nabi, Dalileh, Drechsler, Hauke, Pschirer, Johannes, Korn, Franz, Schuler, Nadine, Diez, Stefan, Jessberger, Rolf, Chacón, Mariola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586017/ https://www.ncbi.nlm.nih.gov/pubmed/34764261 http://dx.doi.org/10.1038/s41467-021-26826-3 |
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