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Deciphering cell lineage specification of human lung adenocarcinoma with single-cell RNA sequencing

Lung adenocarcinomas (LUAD) arise from precancerous lesions such as atypical adenomatous hyperplasia, which progress into adenocarcinoma in situ and minimally invasive adenocarcinoma, then finally into invasive adenocarcinoma. The cellular heterogeneity and molecular events underlying this stepwise...

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Detalles Bibliográficos
Autores principales: Wang, Zhoufeng, Li, Zhe, Zhou, Kun, Wang, Chengdi, Jiang, Lili, Zhang, Li, Yang, Ying, Luo, Wenxin, Qiao, Wenliang, Wang, Gang, Ni, Yinyun, Dai, Shuiping, Guo, Tingting, Ji, Guiyi, Xu, Minjie, Liu, Yiying, Su, Zhixi, Che, Guowei, Li, Weimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586023/
https://www.ncbi.nlm.nih.gov/pubmed/34764257
http://dx.doi.org/10.1038/s41467-021-26770-2